Competing Risks Model in Early Screening for Preeclampsia by Biophysical and Biochemical Markers

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Competing risks model in early screening for preeclampsia by biophysical and biochemical markers.

OBJECTIVE To develop models for prediction of preeclampsia (PE) based on maternal characteristics, biophysical and biochemical markers at 11-13 weeks' gestation in which the gestation at the time of delivery for PE is treated as a continuous variable. METHODS This was a screening study of singleton pregnancies at 11-13 weeks including 1,426 (2.4%) that subsequently developed PE and 57,458 tha...

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Competing risks model in screening for preeclampsia by biophysical and biochemical markers at 30-33 weeks' gestation.

OBJECTIVE To assess the risk for preeclampsia (PE) by maternal characteristics, uterine artery pulsatility index (Ut-PI), mean arterial pressure (MAP), serum placental growth factor (PlGF) and soluble fms-like tyrosine kinase-1 (sFlt-1) at 30-33 weeks' gestation. METHODS This was a screening study in singleton pregnancies including 2,140 that developed PE and 83,615 that were unaffected by PE...

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A competing risks model in early screening for preeclampsia.

OBJECTIVE It was the aim of this study to develop models for the prediction of preeclampsia (PE) based on maternal characteristics and biophysical markers at 11-13 weeks' gestation in which gestation at the time of delivery for PE is treated as a continuous variable. METHODS This was a screening study of singleton pregnancies at 11-13 weeks including 1,426 (2.4%) cases that subsequently devel...

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Competing risks model in screening for preeclampsia by maternal characteristics and medical history.

OBJECTIVE The purpose of this study was to develop a model for preeclampsia based on maternal demographic characteristics and medical history. STUDY DESIGN This was a screening study of 120,492 singleton pregnancies at 11-13 weeks' gestation, including 2704 pregnancies (2.2%) that experienced preeclampsia. A survival-time model for the gestational age at delivery with preeclampsia was develop...

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Competing risks model in screening for preeclampsia by maternal factors and biomarkers at 19-24 weeks' gestation.

BACKGROUND Preeclampsia (PE) affects 2-3% of all pregnancies and is a major cause of maternal and perinatal morbidity and mortality. The traditional approach to screening for PE is to use a risk-scoring system based on maternal demographic characteristics and medical history (maternal factors), but the performance of such an approach is very poor. OBJECTIVE To develop a model for PE based on ...

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ژورنال

عنوان ژورنال: Fetal Diagnosis and Therapy

سال: 2012

ISSN: 1015-3837,1421-9964

DOI: 10.1159/000341264